How may peripheral neuropathy present in a patient with CKD?

In patients with chronic kidney disease (CKD), peripheral neuropathy can manifest in various ways, and restless legs syndrome is one of the common presentations. It is characterized by an uncontrollable urge to move the legs, often accompanied by uncomfortable sensations such as tingling, burning, or itching, which typically worsen during periods of inactivity and improve with movement. This symptom is often seen in the context of uremia, where the accumulation of toxins that are normally cleared by the kidneys affects nerve function.

Restless legs syndrome in CKD can be particularly troublesome for patients, impacting their sleep quality and overall well-being. Understanding this manifestation helps healthcare providers anticipate and manage complications associated with CKD. Other symptoms of peripheral neuropathy can include numbness or tingling, but the classic restless legs sensation is notably significant in this context.